In any country the demand for health services is unlimited and public resources are scarce. Hence, policymaker’s goal is to optimize the effectiveness of a limited healthcare budget. Cost-effectiveness thresholds can be applied to make binary decisions around whether or not to fund a healthcare intervention and ensure decisions will improve net population health. This webinar Jessica O. will explain why cost-effectiveness thresholds play such a relevant role in the decision-making process? How to use them in practice? And which countries have benefited from them?